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Discussion The results of the histological studies revealed that with increasing dose of Sildenafil citrate consumption, there were varying degrees of dilatations of the central vein of the liver which contained lysed red blood cells in the treatment group compared to the control sections of the liver, and as well as varying degree of cyto-architectural distortion and reduction in the number of renal corpuscle in the kidneys of the treated groups compared to the control sections of the kidneys.It may be inferred from the present results that higher doses of Sildenafil citrate consumption may have resulted in degenerative and atrophic changes observed in the renal corpuscle. cialis online.